The final diagnosis is Castleman lymhadenopathy, hyaline-vascular variant. Castleman's disease (CD), also called angiofollicular lymph node hyperplasia, comprises at least two distinct forms, unicentric (UCD) and multicentric (MCD). Its pathologic ...

Idiopathic multicentric Castleman disease (iMCD) is a subtype of Castleman disease (also known as giant lymph node hyperplasia, lymphoid hamartoma, or angiofollicular lymph node hyperplasia), a group of lymphoproliferative disorders characterized by lymph ...

We concluded that this patient suffered from HHV-8 negative multicentric Castleman’s disease. Treatment was initiated with corticosteroids, anti-CD 20 therapy with rituximab and cyclophosphamide. In our case, due to the absence of monotypic deposits ...

In this report, we described both Castleman's disease and lymphoma coexisting in one patient with SIADH. Case presentation: A 70-year-old Chinese woman with a history of diabetes mellitus and ...

However, lymph node biopsy showed interfollicular plasmacytosis, associated with high interleukin 6 (IL-6) and vascular endothelial growth factor titers, together hinting towards a rare diagnosis of multicentric Castleman’s disease (MCD). As we ...

Objectives Differentiating IgG4-related disease (IgG4-RD) from multicentric Castleman’s disease (MCD) is challenging because both diseases present high serum IgG4. The objective of this study is to clarify the differences in characteristics and identify ...

Unicentric Castleman disease is a subtype of Castleman disease (also known as giant lymph node hyperplasia, lymphoid hamartoma, or angiofollicular lymph node hyperplasia), a group of lymphoproliferative disorders characterized by lymph node enlargement ...

Multicentric Castleman's disease is a rare lymphoproliferative disorder of the plasma cell type, which has been reported in both HIV-seropositive and HIV-seronegative patients, and which frequently contains HHV8 DNA. Pleural effusion lymphoma, or body ...

Objectives Castleman’s disease (CD) is a benign lymphoproliferative disease, which usually shows hypermetabolism on FDG PET. Here, we assessed metabolic characteristics of CD in a consecutive series of patients and we compared imaging features of FDG PET ...

Other Diseases Caused by KSHV Figure 3. Figure 3. Pathological and Imaging Findings in KSHV-Associated Multicentric Castleman’s Disease and Primary Effusion Lymphoma. KICS, a syndrome ...

Continuous overproduction of IL6 is observed in patients with some immune-inflammatory diseases such as Castleman's disease and rheumatoid arthritis that are frequently associated with similar abnormalities to those of IL6 transgenic mice, strongly ...

You will be able to get a quick price and instant permission to reuse the content in many different ways. Editor,—Kimura’s disease is a chronic inflammatory disorder of unknown aetiology.1 Patients usually present with recurrent painless swellings in ...

The five stages of Parkinson's disease come on slowly, with symptoms developing and worsening over several years. Patti Greco is a writer and editor whose work has appeared in Glamour, Cosmo ...

hyms.ac.uk Objectives UK guidelines recommend palliative care access for people with Parkinson’s disease; however, this remains sporadic, and it is unknown whether specialist palliative care helps patients and carers cope with this distressing condition.

Crohn’s disease causes chronic inflammation and erosion of the intestines or bowel. There are five types of Crohn’s disease, each affecting different parts of the digestive tract and involving ...

The most common neurodegenerative disease, Alzheimer's disease constitutes about two thirds of cases of dementia overall (ranging in various studies from 42 to 81 percent of all dementias), with ...

A systematic review and meta-analysis were conducted to quantify the efficacy of transcranial magnetic stimulation (TMS) and electroconvulsive therapy (ECT) for the treatment of motor dysfunction in patients with Parkinson’s disease (PD). Prospective ...

Parkinson's disease is caused by a loss of nerve cells in part of the brain called the substantia nigra. This leads to a reduction in a chemical called dopamine in the brain. Dopamine plays a vital role in regulating the movement of the body. A reduction ...

Dr. David Fajgenbaum has played a vital role researching Castleman Disease – a rare, life-threatening disorder – for several years. It's a disease he ...