Summary
Nicotinamide mononucleotide (NMN) is a nucleotide derived from ribose, nicotinamide, nicotinamide riboside and niacin.
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It is converted into nicotinamide adenine dinucleotide (NAD+) within cells
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, which is an essential enzyme for various critical cell functions, including metabolism, DNA repair, cell growth and survival.
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NMN has been gaining attention from the scientific community as an anti-aging health product
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, but there is a lack of clinical safety and efficacy studies.
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Summary
Nicotinamide mononucleotide (NMN) has been gaining attention from the scientific community, and this article provides an overview of the current knowledge on the promises and safety concerns of NMN as an anti-aging health product. In vivo studies have indicated affirmative results of therapeutic effects for various age-induced complications with NMN supplementation, but there is a lack of clinical safety and efficacy studies and proper clinical investigations are urgently needed to find out the effectiveness and safety of NMN supplementation.
Nicotinamide mononucleotide (NMN) as an anti-aging health product ...
sciencedirect.com
Summary
Nicotinamide mononucleotide is a nucleotide derived from ribose, nicotinamide, nicotinamide riboside and niacin. In humans, several enzymes use NMN to generate nicotinamide adenine dinucleotide (NADH). In mice, it has been proposed that NMN is absorbed via the small intestine within 10 minutes of oral uptake and converted to nicotinamide adenine dinucleotide (NAD+) through the Slc12a8 transporter. However, this observation has been challenged, and the matter remains unsettled.
Nicotinamide mononucleotide - Wikipedia
wikipedia.org
