Metformin appears to reduce the risk of Parkinson's Disease in diabetes patients, as well as improve some aging outcomes associated with PD.
It may also target most pathological mechanisms involved in PD.
Additionally, there is a comorbidity of Parkinson's Disease and diabetes.
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We posit that another well-established, well-tolerated anti-diabetic drug, metformin, with a long-established safety record should be also investigated in PD. Preclinical studies have shown that metformin may target most pathological mechanisms involved in PD and improve some aging outcomes.
Metformin as a Potential Neuroprotective Agent in Prodromal Parkinson's ...
Introduction. Epidemiological surveys show that PD is the second most common neurodegenerative disease after Alzheimer's...
Database search strategy. The authors included studies that discussed the potential role of metformin in the treatment...
Comorbidity of Parkinson's disease and diabetes. As...
The potential role of metformin in the treatment of Parkinso ... - LWW
The neuroscientists at the University of Tübingen have identified a protein that plays an important role in the energy balance of cells. If the protein is missing, the energy balance…
Metformin may help in Parkinson’s Disease