Metformin may cause modest weight loss by lowering insulin levels and improving insulin resistance
, and may also interfere with the gut microbiota, prompt the release of appetite-suppressing hormones, and affect appetite-regulating parts of the brain.
It may also raise the body’s levels of the hormone leptin, which makes you feel full.
People with type 2 diabetes and those who are overweight or obese and have insulin resistance have lost weight while taking metformin.
To maximize the effects of metformin, it is recommended to follow a healthful diet and exercise regularly.
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Metformin may interfere with the gut microbiota, prompt the release of appetite-suppressing hormones, and affect appetite-regulating parts of the brain.
Some people who take metformin may also experience diarrhea, bloating, and nausea. These side effects may reduce how much a person wishes to eat.
Metformin and Weight Loss: What You Should Know - Healthline
People who lost weight on metformin continued to lose pounds after that time.
A more likely explanation is that metformin’s changes in the gut tamp down appetite. It may raise the body’s levels of the hormone leptin , which makes you feel full. Since your appetite isn’t working overtime, you eat less.
Does Metformin Cause Weight Loss? - WebMD
Metformin wasn't designed to be a weight loss drug, but researchers have found a link between the drug and weight loss. Past research concluded the drug could serve as a treatment for excess body weight, although more studies are needed.
Metformin Weight Loss: The Truth Behind the Side Effect
People with type 2 diabetes have lost weight from taking metformin, but they are not the only ones to benefit from the drug in this way.
A study involving people who were overweight or obese and had insulin resistance showed that they lost weight while taking metformin.
Metformin and weight loss: Does this drug help? - Medical News Today