is there a genetic link to depression

Summary

Scientists believe that as many as 40 percent of those with depression can trace it to a genetic link 1 , while environmental and other factors may make up the other 60 percent. 1 Twin and family studies suggest that heritability is around 40% to 50% 2 3 , and may be even higher for severe depression. 4 Genome studies have identified 178 gene variants linked to major depression 2 , and people with a higher genetic risk can take protective factors such as cultivating the right home environment, getting enough sleep, and eating nutritious foods. 3

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Summary Scientists believe that as many as 40 percent of those with depression can trace it to a genetic link. Environmental and other factors may make up the other 60 percent. A person who grows up with someone with depression may be more susceptible to the condition.
Is Depression Genetic or Environmental? - Healthline
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healthline.com

Summary Heritability is probably 40-50%, and might be higher for severe depression. This could mean that in most cases of depression, around 50% of the cause is genetic, and around 50% is unrelated to genes (psychological or physical factors).
Major Depression and Genetics - Genetics of Brain Function
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stanford.edu

A threefold approach comprising the combination of gene association studies, assessment of the epigenetic state in DD patients, and analysis of different “omic” changes in animal depression models will make…
Genetics Factors in Major Depression Disease - PMC - PubMed Central (PMC)
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nih.gov

Summary Depression is a common mental health condition that runs in families, but not necessarily means you will inherit it. Twin and family studies suggest that heritability is around 40% to 50%, and may be even higher for severe depression. Genome studies have identified 178 gene variants linked to major depression, and people with a higher genetic risk can take protective factors such as cultivating the right home environment, getting enough sleep, and eating nutritious foods.
Is Depression Genetic? Causes and Contributing Factors
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psychcentral.com

A massive study of genetic and health records of 1.2 million people from four separate data banks has identified 178 gene variants linked to major depression. A massive genome-wide association…
Roots of major depression revealed in all their genetic complexity
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yale.edu

Having a genetic predisposition to depression can exacerbate these factors and may influence when someone becomes depressed as well as how long symptoms may last. However, it’s important to remember…
Can Genetics Cause Depression? - Verywell Mind
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verywellmind.com

For example, it’s been hypothesized that genes associated with low levels of the neurotransmitters serotonin, norepinephrine, and dopamine can lead to the development of depression . 3 These neurotransmitters are responsible…
Is Depression Genetic? - Verywell Health
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verywellhealth.com