Summary
Transdermal hormone therapy may have less pronounced effects on hepatic protein synthesis, such as inflammatory markers, markers of coagulation and fibrinolysis, and steroid binding proteins, while oral hormone therapy has more pronounced hyper-coagulant effects and increases synthesis of C-reactive protein and fibrinolytic markers.
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The transdermal route is the best route for hormone replacement, as it allows for lower doses and a decreased risk of gallbladder disease.
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Summary
When administering hormones, it is important to consider the first pass effect of the hormone, which is the reduction of the effective dose. The transdermal route is the best route for hormone replacement, as it allows for lower doses and a decreased risk of gallbladder disease. It is important to consult a healthcare provider to determine the best route for hormone replacement, as it can help to determine the best dosage for the individual.
Transdermal or Oral - Which is better for hormone administration?
npwomenshealthcare.com
Sexual function was assessed by scores comparing desire, arousal, lubrication, pain, satisfaction, and orgasm. What did we learn? The group using estradiol patches had a 7.2% improvement in their scores…
Patch vs Pills for Estrogen Replacement - GoodRx
goodrx.com
