Citrulline is an amino acid found in watermelon 1 and is considered nonessential, meaning that the body can produce some on its own. 1 It is one of the three dietary amino acids in the urea cycle 2 and is also produced as a byproduct of the enzymatic production of nitric oxide from the amino acid arginine. 3 Citrulline has the formula H2NC(O)NH(CH2)3CH(NH2)CO2H 3 and is a key intermediate in the urea cycle, the pathway by which mammals excrete ammonia by converting it into urea. 3

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Summary Citrulline is an amino acid that was first found in watermelon ( 1 ). It is considered nonessential, meaning that your body can naturally produce some on its own.
Should You Take Citrulline Supplements? - Healthline

Summary What is citrulline? Citrulline is one of the three dietary amino acids in the urea cycle (the other two are L-arginine and L-ornithine ). Taking citrulline increases plasma levels of arginine and improves the ammonia recycling process and nitric oxide metabolism.
Citrulline — Health benefits, dosage, safety, side-effects, and more ...

Citrulline , also commonly referred to as L- citrulline , is a non-essential amino acid. It’s considered non-essential because your body makes it on its own, specifically in the liver and...
Citrulline: Health Benefits, Potential Risks, Dosage, and More - WebMD

The name citrulline comes from Citrullus vulgaris, the Latin term for watermelon. Unlike some amino acids, L- citrulline isn't used to make protein, but it might help increase other chemicals...
L-CITRULLINE - Uses, Side Effects, and More - WebMD

The organic compound citrulline is an α-amino acid. Its name is derived from citrullus , the Latin word for watermelon . Although named and described by gastroenterologists since the late…
Citrulline - Wikipedia

Citrulline is a non-essential amino acid that is made in the liver and intestine, but some individuals may take it as a natural supplement for various health and athletic benefits.…
Citrulline: Benefits, Side Effects, Dosage, and Interactions

Supplements and Dosage Info. Risks, Side Effects and Interactions. Citrulline is an amino acid often used to improve overall health and ramp up your fitness routine. Although it’s not considered…
Citrulline Benefits, Foods, Supplements and Side Effects - Dr. Axe

L- citrulline is a naturally occurring amino acid found in food, such as watermelons, and also made in the body. Our bodies change L- citrulline into another amino acid called L-arginine and…
L-citrulline: Health Benefits, Side Effects, Uses, Dose ... - RxList