Summary
Amlodipine has an elimination half life of 30 to 50 hours
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, which means it takes about 5.5 elimination half lives for a medicine to be out of your system.
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It is taken by mouth
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and is a low-clearance, dihydropyridine calcium antagonist.
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Side effects, dosage, and other considerations should be taken into account before taking amlodipine.
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According to
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Summaries from the best pages on the web
Summary
Amlodipine is a low-clearance, dihydropyridine calcium antagonist. The slow rate of elimination (elimination half-life of 40-60 h) confers several pharmacokinetic characteristics that are not seen with other calcium-antagonist drugs.
Pharmacokinetics and pharmacodynamics of amlodipine
nih.gov
Amlodipine has been studied in healthy volunteers following oral administration of 14 C-labelled drug. Amlodipine is well absorbed by the oral route with a mean oral bioavailability around 60%; the…
Amlodipine - Wikipedia
wikipedia.org
Compared to nifedipine and other medications in the dihydropyridine class, amlodipine has the longest half-life at 30 to 50 hours. The benefit of such a long half-life is the ability…
Amlodipine - StatPearls - NCBI Bookshelf
nih.gov
